Expertly Crafted 300+ DNP Project Ideas: Nursing Research Guide

DNP research projects are scholarly investigations that allow DNP students to apply their advanced knowledge and skills to address real-world problems in healthcare settings. These projects are designed to improve patient outcomes, enhance healthcare delivery systems, or promote the implementation of evidence-based practices. This article aims to provide a comprehensive list of 300+ DNP project ideas, categorized by key areas in nursing practice. This list aims to inspire and guide DNP students in selecting impactful and feasible projects that align with their professional goals and the needs of their patient populations.

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Importance of DNP Projects

Doctor of Nursing Practice (DNP) projects are crucial for advancing nursing practice and improving healthcare outcomes. These doctoral projects bridge the gap between research and clinical practice, ensuring that new knowledge and evidence-based practices are integrated into patient care. DNP projects not only enhance the skills and knowledge of nurses but also contribute to the broader field of healthcare by addressing pressing clinical issues, improving patient outcomes, and optimizing healthcare delivery systems.

Overview of Diverse DNP Project Ideas

DNP project ideas can span a wide range of topics, reflecting the diverse challenges and opportunities within healthcare. These projects can focus on clinical practice improvements, patient safety initiatives, healthcare technology integration, policy advocacy, leadership development, education, and more. Each area offers numerous opportunities for innovation and impact, allowing DNP students to tailor their projects to their interests and the needs of their communities.

Brief Mention of Key Areas in Nursing Practice

Key areas in nursing practice that often serve as focal points for DNP projects include:

  • Reducing hospital-acquired infections
  • Improving patient safety measures
  • Enhancing chronic disease management
  • Optimizing pain management protocols
  • Implementing evidence-based nursing practices
  • Streamlining emergency room procedures
  • Improving post-operative care
300+ DNP project ideas

The following sections list ideal ideas across different focal points in nursing practice that you can consider for your DNP project. 

Reducing Hospital-Acquired Infections

  1. Implementing hand hygiene programs in healthcare settings.
  2. Developing infection control protocols for catheter-associated urinary tract infections (CAUTIs).
  3. Designing interventions to reduce ventilator-associated pneumonia (VAP).
  4. Establishing guidelines for preventing surgical site infections (SSIs).
  5. Enhancing cleaning and disinfection practices for hospital environments.
  6. Creating antimicrobial stewardship programs to reduce antibiotic resistance.
  7. Implementing isolation protocols for patients with multidrug-resistant organisms (MDROs).
  8. Developing strategies to prevent Clostridioides difficile infections.
  9. Improving compliance with central line-associated bloodstream infection (CLABSI) prevention measures.
  10. Designing educational programs for healthcare workers on infection prevention.

Improving Patient Safety Measures

  1. Implementing medication reconciliation programs to reduce errors.
  2. Developing fall prevention strategies for hospitalized patients.
  3. Enhancing surgical safety through the use of checklists.
  4. Creating a culture of safety in healthcare organizations.
  5. Designing programs to reduce pressure ulcers in bedridden patients.
  6. Establishing protocols for safe patient handling and mobility.
  7. Improving communication during patient handoffs.
  8. Developing alarm management strategies to reduce alarm fatigue.
  9. Enhancing the use of barcoding for medication administration.
  10. Implementing electronic health record (EHR) alerts for potential safety issues.

Enhancing Chronic Disease Management

  1. Developing care coordination programs for patients with multiple chronic conditions.
  2. Implementing self-management education programs for diabetes.
  3. Enhancing heart failure management through telemonitoring.
  4. Designing interventions to improve asthma control in children.
  5. Creating comprehensive care plans for patients with chronic obstructive pulmonary disease (COPD).
  6. Developing support groups for patients with chronic pain.
  7. Implementing lifestyle modification programs for obesity.
  8. Enhancing adherence to hypertension treatment protocols.
  9. Designing educational materials for patients with chronic kidney disease.
  10. Improving management of patients with rheumatoid arthritis.

Optimizing Pain Management Protocols

  1. Developing opioid-sparing pain management strategies.
  2. Implementing multimodal analgesia for post-operative pain.
  3. Enhancing the use of non-pharmacological pain management techniques.
  4. Creating pain management education programs for nurses.
  5. Designing protocols for the safe use of patient-controlled analgesia.
  6. Improving pain assessment practices in non-verbal patients.
  7. Developing guidelines for managing chronic pain in primary care.
  8. Implementing interventions to reduce pain in cancer patients.
  9. Enhancing pain management in palliative care settings.
  10. Designing strategies to address pain management disparities.
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Implementing Evidence-Based Nursing Practices

  1. Developing protocols for evidence-based wound care.
  2. Implementing evidence-based guidelines for sepsis management.
  3. Enhancing the use of evidence-based practices in pediatric care.
  4. Creating evidence-based protocols for delirium prevention in ICU patients.
  5. Developing guidelines for managing patients with congestive heart failure.
  6. Implementing evidence-based practices for stroke rehabilitation.
  7. Enhancing adherence to evidence-based asthma management guidelines.
  8. Designing interventions to improve evidence-based practice in home health care.
  9. Developing evidence-based protocols for managing patients with dementia.
  10. Implementing strategies to promote evidence-based practices among nursing staff.

Streamlining Emergency Room Procedures

  1. Implementing triage protocols to reduce emergency room wait times.
  2. Developing strategies to improve patient flow in the emergency department.
  3. Enhancing communication between emergency room staff and other departments.
  4. Creating protocols for managing psychiatric emergencies.
  5. Implementing interventions to reduce overcrowding in emergency rooms.
  6. Developing guidelines for managing pain in emergency room patients.
  7. Enhancing the use of telemedicine in emergency care.
  8. Creating educational programs for emergency room nurses on trauma care.
  9. Implementing strategies to improve patient satisfaction in emergency settings.
  10. Developing protocols for the rapid assessment and treatment of stroke patients.

Improving Post-Operative Care

  1. Implementing enhanced recovery after surgery (ERAS) protocols.
  2. Developing guidelines for post-operative pain management.
  3. Enhancing monitoring of post-operative patients to prevent complications.
  4. Creating education programs for patients on post-operative care.
  5. Implementing strategies to reduce post-operative infections.
  6. Developing protocols for managing post-operative nausea and vomiting.
  7. Enhancing coordination of care during the post-operative period.
  8. Creating discharge planning programs for surgical patients.
  9. Implementing interventions to improve post-operative mobility.
  10. Designing strategies to enhance patient adherence to post-operative care instructions.

Patient Education and Engagement

Developing Patient Education Programs

  1. Creating comprehensive diabetes education programs.
  2. Developing educational materials for patients with heart disease.
  3. Implementing programs to improve asthma management in children.
  4. Designing educational interventions for patients with chronic pain.
  5. Creating programs to enhance understanding of hypertension management.
  6. Developing educational resources for patients with cancer.
  7. Implementing smoking cessation programs.
  8. Enhancing patient education on medication adherence.
  9. Creating educational programs for post-operative care.
  10. Developing resources to improve nutrition and diet management.

Enhancing Health Literacy

  1. Implementing health literacy assessments in clinical settings.
  2. Developing plain language educational materials for patients.
  3. Enhancing communication strategies to improve health literacy.
  4. Creating programs to teach patients how to navigate the healthcare system.
  5. Implementing interventions to improve health literacy in underserved populations.
  6. Designing educational tools to enhance understanding of medical conditions.
  7. Developing strategies to improve medication literacy.
  8. Creating health literacy workshops for community members.
  9. Enhancing the use of visual aids in patient education.
  10. Implementing programs to improve digital health literacy.

Creating Mobile Health Applications

  1. Developing mobile apps for diabetes self-management.
  2. Creating apps to track and manage hypertension.
  3. Implementing mobile solutions for medication reminders.
  4. Designing apps for mental health support.
  5. Enhancing mobile platforms for weight management.
  6. Developing apps to improve physical activity.
  7. Creating mobile tools for smoking cessation.
  8. Implementing apps for chronic pain management.
  9. Designing mobile solutions for post-operative care.
  10. Enhancing patient engagement through health tracking apps.

Designing Patient-Centered Care Plans

  1. Developing individualized care plans for patients with multiple chronic conditions.
  2. Implementing patient-centered care models in primary care.
  3. Creating care plans that address social determinants of health.
  4. Enhancing care coordination through patient-centered plans.
  5. Designing care plans that incorporate patient preferences and values.
  6. Developing family-centered care plans for pediatric patients.
  7. Implementing care plans for end-of-life care.
  8. Creating patient-centered approaches for mental health care.
  9. Enhancing care plans for patients with dementia.
  10. Developing culturally sensitive care plans.

Improving Patient Adherence to Treatment

  1. Implementing reminder systems to enhance medication adherence.
  2. Developing motivational interviewing techniques to improve adherence.
  3. Creating educational programs to enhance understanding of treatment plans.
  4. Implementing strategies to reduce barriers to adherence.
  5. Designing interventions to improve adherence to lifestyle modifications.
  6. Enhancing support systems for patients with chronic conditions.
  7. Developing apps to track and remind patients of their treatments.
  8. Creating personalized adherence plans for patients.
  9. Implementing peer support programs to improve adherence.
  10. Designing strategies to address non-adherence in pediatric populations.

Implementing Telehealth Solutions

  1. Developing telehealth programs for rural healthcare delivery.
  2. Implementing telepsychiatry services for mental health support.
  3. Enhancing telehealth for chronic disease management.
  4. Creating telehealth solutions for post-operative follow-up.
  5. Developing telehealth platforms for primary care.
  6. Implementing telehealth interventions for diabetes management.
  7. Enhancing telehealth services for geriatric care.
  8. Creating telehealth programs for maternal and child health.
  9. Developing telehealth solutions for emergency care.
  10. Implementing telehealth for patient education and engagement.

Enhancing Patient Communication Strategies

  1. Developing communication skills training programs for healthcare providers.
  2. Implementing teach-back methods to ensure patient understanding.
  3. Enhancing the use of communication technologies in healthcare.
  4. Creating communication protocols for end-of-life discussions.
  5. Developing strategies to improve communication with non-English speaking patients.
  6. Implementing patient portals to enhance communication.
  7. Enhancing communication during care transitions.
  8. Creating strategies to improve communication between patients and care teams.
  9. Implementing programs to enhance communication with patients with low health literacy.
  10. Developing protocols for effective communication in telehealth settings.
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Healthcare Technology Integration

Utilizing Electronic Health Records (EHR)

  1. Enhancing EHR training programs for healthcare providers.
  2. Developing strategies to improve EHR usability.
  3. Implementing protocols to ensure data accuracy in EHRs.
  4. Enhancing the use of EHRs for care coordination.
  5. Developing interventions to improve EHR documentation practices.
  6. Implementing EHR-based decision support systems.
  7. Creating programs to optimize the use of EHRs in primary care.
  8. Enhancing patient access to EHRs.
  9. Developing strategies to improve EHR interoperability.
  10. Implementing EHR solutions for telemedicine.

Implementing Clinical Decision Support Systems

  1. Developing algorithms for clinical decision support.
  2. Implementing decision support tools for medication management.
  3. Enhancing the use of decision support in chronic disease management.
  4. Creating decision support systems for diagnostic accuracy.
  5. Developing tools to support evidence-based practice through decision support.
  6. Implementing clinical decision support in emergency care.
  7. Enhancing decision support for preventive care.
  8. Creating decision support systems for patient safety.
  9. Developing personalized decision support tools.
  10. Implementing decision support systems for surgical care.

Enhancing Telemedicine Services

  1. Developing telemedicine programs for specialty care.
  2. Implementing telehealth solutions for remote patient monitoring.
  3. Enhancing the use of telemedicine in rural healthcare settings.
  4. Creating telehealth interventions for chronic disease management.
  5. Implementing telemedicine services for mental health care.
  6. Developing telehealth solutions for pediatric care.
  7. Enhancing telemedicine for post-operative follow-up.
  8. Creating telehealth programs for preventive care.
  9. Implementing telehealth solutions for elderly care.
  10. Enhancing telemedicine for infectious disease management.

Developing Remote Monitoring Systems

  1. Implementing remote monitoring for diabetes management.
  2. Developing systems for heart failure monitoring.
  3. Enhancing remote monitoring for hypertension.
  4. Creating solutions for remote monitoring of respiratory conditions.
  5. Implementing remote monitoring for post-operative care.
  6. Developing remote monitoring systems for maternal health.
  7. Enhancing remote monitoring for chronic pain management.
  8. Creating remote monitoring programs for pediatric care.
  9. Implementing remote monitoring for mental health conditions.
  10. Developing remote monitoring systems for cancer patients.

Improving Health Information Exchange (HIE)

  1. Developing strategies to enhance HIE participation.
  2. Implementing protocols to improve HIE data quality.
  3. Enhancing the use of HIE for care coordination.
  4. Creating programs to promote HIE adoption among healthcare providers.
  5. Developing interventions to improve HIE interoperability.
  6. Implementing HIE solutions for population health management.
  7. Enhancing patient access to HIE data.
  8. Creating tools to support HIE integration with EHRs.
  9. Developing strategies to address HIE privacy and security concerns.
  10. Implementing HIE for emergency care.

Leveraging Big Data in Nursing

  1. Developing big data analytics for population health.
  2. Implementing big data solutions for chronic disease management.
  3. Enhancing the use of big data in predictive analytics.
  4. Creating big data programs for quality improvement.
  5. Developing interventions to leverage big data for patient safety.
  6. Implementing big data analytics for nursing research.
  7. Enhancing the use of big data in healthcare decision-making.
  8. Creating big data solutions for personalized care.
  9. Developing strategies to integrate big data into clinical practice.
  10. Implementing big data for health policy analysis.

Advancing Mobile Health Technologies

  1. Developing mobile health apps for patient engagement.
  2. Implementing mobile solutions for remote monitoring.
  3. Enhancing mobile health technologies for chronic disease management.
  4. Creating mobile health interventions for preventive care.
  5. Developing mobile health solutions for mental health support.
  6. Implementing mobile health apps for medication adherence.
  7. Enhancing mobile health technologies for maternal and child health.
  8. Creating mobile solutions for health education.
  9. Developing mobile health apps for lifestyle management.
  10. Implementing mobile health technologies for elderly care.

Quality Improvement and Safety Initiatives

Reducing Medication Errors

  1. Implementing barcode medication administration systems.
  2. Developing strategies to improve medication reconciliation.
  3. Enhancing the use of clinical decision support for medication safety.
  4. Creating educational programs on safe medication practices.
  5. Implementing protocols to reduce high-alert medication errors.
  6. Developing interventions to improve pediatric medication safety.
  7. Enhancing pharmacist-led medication reviews.
  8. Creating tools to support medication error reporting.
  9. Implementing strategies to improve communication about medications.
  10. Developing systems to track and analyze medication errors.

Improving Hand Hygiene Compliance

  1. Implementing hand hygiene campaigns in healthcare settings.
  2. Developing educational programs on hand hygiene.
  3. Enhancing hand hygiene monitoring and feedback systems.
  4. Creating incentives for hand hygiene compliance.
  5. Implementing technology solutions to support hand hygiene.
  6. Developing strategies to improve hand hygiene in outpatient settings.
  7. Enhancing hand hygiene practices in home healthcare.
  8. Creating visual aids and reminders for hand hygiene.
  9. Implementing hand hygiene protocols for visitors.
  10. Developing interventions to address hand hygiene barriers.

Enhancing Surgical Safety

  1. Implementing surgical safety checklists.
  2. Developing protocols for preventing surgical site infections.
  3. Enhancing communication and teamwork in the operating room.
  4. Creating educational programs on surgical safety.
  5. Implementing strategies to reduce wrong-site surgery.
  6. Developing interventions to improve surgical handoff communication.
  7. Enhancing monitoring of surgical patients.
  8. Creating systems to track surgical outcomes.
  9. Implementing protocols to ensure surgical instrument sterilization.
  10. Developing strategies to improve post-operative follow-up.

Developing Infection Control Programs

  1. Implementing infection control protocols for healthcare-associated infections.
  2. Developing educational programs on infection prevention.
  3. Enhancing environmental cleaning and disinfection practices.
  4. Creating systems to monitor and report infection rates.
  5. Implementing protocols for antibiotic stewardship.
  6. Developing strategies to reduce the spread of MDROs.
  7. Enhancing infection control in outpatient settings.
  8. Creating interventions to improve hand hygiene compliance.
  9. Implementing isolation protocols for infectious patients.
  10. Developing programs to improve vaccination rates among healthcare workers.
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Implementing Fall Prevention Strategies

  1. Developing comprehensive fall prevention programs.
  2. Implementing fall risk assessment tools.
  3. Enhancing staff education on fall prevention.
  4. Creating environmental modifications to reduce fall risks.
  5. Implementing patient and family education on fall prevention.
  6. Developing strategies to improve monitoring of high-risk patients.
  7. Enhancing the use of technology to prevent falls.
  8. Creating protocols for post-fall management.
  9. Implementing interventions to reduce falls in home healthcare.
  10. Developing programs to address fall prevention in elderly populations.

Optimizing Blood Transfusion Practices

  1. Implementing blood transfusion safety protocols.
  2. Developing educational programs on safe transfusion practices.
  3. Enhancing monitoring and reporting of transfusion reactions.
  4. Creating systems to track and analyze transfusion data.
  5. Implementing strategies to reduce unnecessary transfusions.
  6. Developing protocols for patient blood management.
  7. Enhancing the use of technology to improve transfusion safety.
  8. Creating tools to support transfusion decision-making.
  9. Implementing interventions to improve patient education on transfusion.
  10. Developing programs to enhance blood product management.

Enhancing Pressure Ulcer Prevention

  1. Implementing pressure ulcer prevention protocols.
  2. Developing educational programs on pressure ulcer care.
  3. Enhancing the use of pressure-relieving devices.
  4. Creating systems to monitor and report pressure ulcer incidence.
  5. Implementing strategies to improve patient repositioning.
  6. Developing interventions to enhance nutrition for pressure ulcer prevention.
  7. Enhancing skin care practices to prevent pressure ulcers.
  8. Creating protocols for early identification of pressure ulcers.
  9. Implementing interventions to reduce pressure ulcers in at-risk populations.
  10. Developing programs to improve pressure ulcer management in home care.

Health Policy and Advocacy

Influencing Health Policy Reform

  1. Developing advocacy strategies to influence healthcare policy.
  2. Implementing campaigns to support health policy changes.
  3. Enhancing the involvement of nurses in health policy decision-making.
  4. Creating educational programs on health policy for nurses.
  5. Developing interventions to address healthcare disparities through policy.
  6. Implementing strategies to promote health policy research.
  7. Enhancing collaboration between healthcare organizations and policymakers.
  8. Creating tools to support health policy analysis.
  9. Implementing programs to educate the public on health policy issues.
  10. Developing initiatives to improve access to healthcare services.

Promoting Access to Healthcare Services

  1. Implementing programs to improve access to primary care.
  2. Developing interventions to reduce barriers to healthcare access.
  3. Enhancing telehealth services to improve access to care.
  4. Creating programs to support healthcare access in rural areas.
  5. Implementing strategies to improve access to mental health services.
  6. Developing initiatives to enhance access to preventive care.
  7. Enhancing healthcare access for underserved populations.
  8. Creating programs to support healthcare access for immigrants.
  9. Implementing interventions to improve access to specialized care.
  10. Developing policies to address healthcare access disparities.


Embarking on a DNP project is a significant step toward advancing your nursing career and contributing to the healthcare field. With over 300 project ideas spanning various areas of nursing practice, the possibilities for making a meaningful impact are vast. 

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  1. How do I choose a topic for a DNP project? Choose a topic that aligns with your clinical interests, addresses a significant healthcare issue, and has the potential for measurable outcomes. Consult with mentors and review current literature to ensure the topic’s relevance and feasibility.
  2. What is a DNP quality improvement project? A DNP quality improvement project aims to enhance healthcare outcomes by systematically analyzing and improving processes within a healthcare setting, often focusing on patient safety, efficiency, and effectiveness of care.
  3. What are the examples of quality improvement projects in nursing? Examples of quality improvement projects in nursing include reducing hospital readmission rates, implementing fall prevention programs, enhancing hand hygiene compliance, and improving patient satisfaction scores through better communication strategies.

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